We're building an AI-first bioinformatics platform to empower life science researchers with agentic AI and LLMs. Backed by pre-seed funding, a government grant, and customers from biotech, agrotech, and pharma companies, we're looking for a full-stack engineer to join as a core member.
What we're looking for:
• Strong full-stack experience across Go, TypeScript, and Python (Rust is a plus)
• Hands-on AWS infrastructure work (you've built and maintained production cloud environments)
• Experience with multi-tenant architectures: isolation strategies, auth, data partitioning
• Comfort with AI/ML devops: deploying and orchestrating model-serving pipelines, managing GPU workloads, CI/CD for ML systems
• Willingness to own problems end-to-end, from system design to shipping
Nice-to-haves (not all required): LLM integration, RAG systems, HPC infra, cloud/on-prem hybrid systems
About us: We're a team of engineers and scientists with strong academic and industry backgrounds (ex-BCG, PhD in Plant Biotech and Bioinformatics, Mathematics, M.Sc. AI, PhD in Electrical Engineering). We're committed to building something impactful, technical, and genuinely useful for life science.
Apply: hello@ploid.ai
More about us: https://ploid.ai
We also consider internship requests from strong student candidates for research work.
Thanks to everyone who's reached out through previous HN posts, this community has helped us find amazing people.
Fullstory offers privacy-preserving session replay and analytics for websites and mobile apps. Our session replays are nothing short of magical, and the combination with our automatic analytics creates eye-opening insights.
Atlanta, US engineering roles (semi-onsite, requiring 1 day per week in office):
* Senior Software Engineer, Web Capture - $145~170k + up to 10% bonus - JavaScript/TypeScript, React, Go (golang) - https://www.fullstory.com/careers/jobs/76e583a9-74c0-42d4-ae...
* Senior Software Engineer, Data Pipeline - $160~180k USD + up to 10% bonus - Go (golang), Kubernetes (K8s), GCP - https://www.fullstory.com/careers/jobs/a786962d-68c1-48fa-8b...
Bogotá, Colombia:
* Senior Software Engineer II, Guides & Surveys - $90~93k USD + up to 10% bonus - https://www.fullstory.com/careers/jobs/073bfc41-0ac6-4e59-a5...
We have additional roles for sales, consulting, HR, accounting, and customer support open in Atlanta, London, and some Remote (US) options. See the full list at https://www.fullstory.com/careers?utm_source=092xpqyAkV
For US roles, you can expect regular raises & bonuses, equity, and benefits including: health insurance, 401k matching (Vanguard), annual learning stipend, unlimited PTO, parental leave, and more. I take about 4-5 weeks vacation a year, in addition to ~3 weeks worth of company holidays (federal holidays + the week of Christmas to New Years.)
Folks in other countries can also expect a strong benefits package, but I'm not as versed on the details.
Additionally, you get a 5-week sabbatical after 5 years of employment - I took mine about a year ago, and it was fantastic.
To apply, please submit your info on the website, and our recruiting team will get in touch with you. If you have questions, feel free to reply here or contact me directly. (I'm an engineer on the iOS team, but I'll do my best to answer questions.)
We're building the Databricks for content production, starting with post. Our orchestration engine coordinates pipelines end to end and turns post-production workflows into a persistent graph of assets and transformations, which are deterministic, verifiable, and nearly instant at scale, powered by a high-performance compute layer. We're building this AI-native from the ground up; ML inference is embedded throughout the pipeline, not bolted on.
Stack: On-prem, HPC clusters, distributed storage systems, GPU pipelines, real-time video compute.
We're looking for our founding senior backend engineer who wants to work on genuinely challenging infrastructure problems across distributed systems and media processing with immense scale. Should be familiar with Golang, Postgres, Distributed systems, Distributed filesystems (e.g. HDFS, Ceph, etc). If that sounds interesting, reach out directly to me at wilson@postup.pro.
Me: https://www.linkedin.com/in/hayswilson/
How to apply: Email me directly at wilson@postup.pro or Submit here - https://www.notion.so/Founding-Senior-Backend-Engineer-31031...
Pinwheel is the Plaid for payroll — APIs and SDKs that give banks, fintechs, and lenders real-time, consumer-permissioned access to payroll data across 1,800 platforms covering 80% of US workers.
- Fullstack Engineer (backend-leaning) - https://grnh.se/y0rp77go3us (Python / Django, Go)
- Fullstack Engineer (frontend-leaning) - https://grnh.se/1e2ort3e3us (React, Next.js)
Hybrid 3x/wk in NYC (Union Square)
Visa sponsorship not available.
We’re open-source, developer-first, and focused on making data movement radically simpler across both our Platform and Applications layers.
We’re hiring for:
Senior Systems Engineer — Capture & Materializations Design and build high-performance connectors that move data in and out of Estuary in real time. Work across APIs, databases, and streaming systems to ensure correctness, reliability, and scalability. This role is deeply systems-oriented, with a focus on data plane execution. Go and Rust are core to our stack.
Senior Systems Engineer — Control & Data Plane Own core infrastructure that orchestrates and powers Estuary’s runtime — from control plane services to distributed data processing systems. Tackle challenges in scaling, fault tolerance, and performance across a globally distributed system. Strong backend fundamentals required; Go and Rust experience preferred.
Solutions Engineer Work with the founding team to help customers use Estuary effectively. Collaborate closely with engineering and product, shape how users integrate real-time data, and feed insights back into product development.
Product Manager Own product areas end-to-end, working closely with engineering and design to shape the roadmap and deliver a great developer experience. Engage with users, translate real-world use cases into product decisions, and help define how modern data infrastructure should feel to build with.
What we’re looking for: Engineers who care about building reliable, maintainable systems and enjoy working with complex APIs and data flows. We value curiosity, clear communication, and a willingness to learn.
Bonus points for experience with CDC tools, open source contributions, or fast-paced startups.
To apply: Email your resume to careers@estuary.dev
BoWatt builds AI software for manufacturing complex hardware products like machines, medical devices or electronics. We’re a profitable, bootstrapped startup headquartered in Munich, with team members across Germany and the UK.
We’re looking for a full-stack engineer to own and ship features across our Go backend and React/TypeScript frontend, with the option to work on our AI features as well. You have to live in Germany and have the right to work here for this role.
We’re a team of eight, and more than half of us are former startup founders (deep tech, AI, psychedelics and gaming). We build closely with our customers and aim to strike the right balance between moving fast and not breaking things.
Reach out directly: fabian@bowatt.com
Hi everyone! We're a Series A startup on a mission to protect society from fraud and money laundering using our intelligent Client Due Diligence Platform. With fraud and money laundering skyrocketing, regulated professionals are struggling to keep pace with their compliance obligations. Thirdfort turns compliance into a competitive advantage, offering beautifully secure onboarding for regulated businesses operating across legal and property.
We've already protected over 3 million people through life's big transactions, with a core aim to protect many more. We've spent the last year rebuilding our product from the ground up and are increasingly leaning into AI across the team/system, focusing on technologies that let product-minded engineers solve hard client problems fast and with confidence: Go, Temporal, NextJS and React Native. We expect our engineers to use their hard-won expertise to get deeply involved in product design as much as technical implementation — joining the team is a great opportunity to work with exciting tech and have a real impact on people's lives.
We have the following open positions:
* Lead Software Engineer – we're looking for a strong technical leader to drive one of our product squads. You'll shape architecture, mentor engineers, and ship meaningful product improvements.
* Senior Software Engineer – we're looking for a senior engineer who's excited to own problems end-to-end, from product design through to production.
* Analytics Engineer (Fixed Term Contract) – we're looking for someone to own and improve our analytics models and datasets end-to-end, covering a period of parental leave.
Come take a look at our open roles: https://www.thirdfort.com/jobs/
Thunder Compute is a GPU cloud for developers built on a proprietary software stack of C++ and GoLang. You will solve hard systems problems in production.
Quant dev / HFT SWE experience preferred, team from CitSec, Aquatic, Old Mission, AWS.
Email me: carl@thundercompute.com
ClickHouse is a popular, Open-Source OLAP Database. We are ClickHouse Inc, the company behind the database aiming to build the best in class real time data warehouse.
I am hiring for AutoScaling as well as Distributed Cache Production Engineer Roles
What we are looking for:
Distributed Systems / Cloud Engineers to build
- AutoScaling Systems for a Cloud Database - A Distributed Caching Layer on top of S3 [0] If you have experience in productionising cloud-based multi-tenant caches - you would fit right in.We also maintain our own ClickHouse-based Data Infrastructure. Bonus points if you've worked on auto-scaling or other data-driven forecasting challenges in the past.
Can work in a fast moving scale-up environment. Proactive and hands on. You must be independent and self-organized. Go, Kubernetes, Distributed Systems in general You'll need to be able to do On-Call - debugging production infra or db issues Low-level database programming (C++, ClickHouse) - This is crucial for the cache. If you want to work on operating production critical databases/caches in the cloud on or write data-driven algorithms for autoscaling, consider applying! Send me an email: manish.gill [at] clickhouse [dot] comPS: If you're a pure DevOps person or a pure Data Engineer who wrangles data tools, please read the above requirements carefully before firing off an email. This role is an intersection of a lot of sub-roles, not a particular specialization
[0] https://clickhouse.com/blog/building-a-distributed-cache-for...
Foxglove is the leading data infrastructure & observability platform for robotics & physical AI.
Prior experience in the autonomous vehicle or robotics industry is a bonus, but not required.
Many open roles:
- Software Engineers (Visualization Engineer, Frontend Engineer, Backend Engineer)
- ML Engineers
- Forward Deployed Engineer (FDE)
- Product Design, Visual Design
- Go To Market
Email in profile.
I'm Alex, founder and CEO of River. I also wrote the first line of code and still ship PRs.
River is a client-first Bitcoin-only financial institution building the financial app people use every day to save in bitcoin and spend in dollars. We custody over 25,000 BTC, serve individuals and businesses across the U.S., and are profitable. We publish cryptographic proof of reserves monthly and our company financials annually.
Here's what our engineering team is working on:
- Real-time Bitcoin and USD payments, trading, and settlement on an Elixir monolith with a unified GraphQL API - Next-generation Bitcoin custody with quorum signing, key ceremonies, and geo-redundant infrastructure - Scaling our ML/AI systems (Python, PyTorch, XGBoost, LLMs) to automate operations and tackle fraud/risk - A ground-up React and React Native rewrite of our consumer app - Porting our Lightning Network infrastructure from Go into Elixir We're hiring: - Senior Software Engineer (React, Full-stack) | $150K-$220K - Staff Software Engineer (Elixir) | $200K-$250K - Staff Software Engineer (ML/AI) | $200K-$250K Apply at https://jobs.ashbyhq.com/river?utm_source=Zp9nJyqvd4Bubblehouse is a fast-growing custom loyalty platform, tripling the revenue each year. Headquartered in NYC, the entire team is fully remote and spread across the globe. We power loyalty programs for brands like American Girl and Old Spice.
We’re expanding our lean team of extremely experienced developers. Companies are switching from other platforms thanks to the customizations and flexibility that we offer, enabled by our pace and technical excellence, which we intend to keep for years to come.
We run on Golang and use custom data storage on top of local key-value stores, colocating the storage and compute on dedicated hardware servers, and reading data directly from mmap’ed pages of the database. Ever came across HN saying that one can run Twitter on a single machine these days? We’re doing that in production.
Zero lines of React, almost zero third-party dependencies (carefully vetted), every line of JavaScript manually written with respect and understanding of the web platform. We render HTML server-side like it’s 2005.
Looking for:
1. Top to bottom understanding of the software stack, from the modern-ish web platform to CPU caches.
2. Thinking and problem solving outside the box. (We don’t _always_ go for unconventional solutions, but we do it often enough to require a person who can do justice considering the entire problem space at every step.)
3. Demonstrated ability and hunger to learn new things quickly. (Every month we’re doing things we have never done before.)
4. Broad experience across multiple programming paradigms, platforms and software stacks.
5. Demonstrated care for the software craftsmanship (which can take many forms).
6. Great spoken English, and ability to communicate 9am to noon in New York time zone.
We give you a literally fast-paced environment (with features delivered in days) where you need to solve very challenging problems with practical advanced technology, take on entrenched market leaders, and help entrepreneurs across small and large businesses delight their fans.
Send a plain text cover letter to andrey+hiring@bubblehouse.com. Help us see how you stand out. Summarize your experience. Link to 1–5 impressive things you’ve built and proud of, link to where we can see some of your code, include your portfolio/CV, describe the platforms and stacks you’re an expert in. How did you start programming? What are you most passionate about in technology? What are the most interesting or weird things you’ve done? What are your strongest held professional opinions? Please make your email easy to read, we’ll appreciate that.
(If you have applied before, no need to re-apply, we’ll reach out.)
We're a VC-funded startup (recently raised $51M Series C) building an infrastructure orchestrator and collaborative management platform for Infrastructure-as-Code – from OpenTofu, Terraform, Terragrunt, CloudFormation, Pulumi, Kubernetes, to Ansible.
On the backend we're using 100% Go with AWS primitives. We're looking for backend developers who like doing DevOps'y stuff sometimes (because in a way it's the spirit of our company), or have experience with the cloud native ecosystem. Ideally you'd have experience working with an IaC tool, i.e. Terraform, Pulumi, Ansible, CloudFormation, Kubernetes, or SaltStack.
Overall we have a deeply technical product, trying to build something customers love to use, and have a lot of happy and satisfied customers. We promise interesting work, the ability to open source parts of the project which don't give us a business advantage, as well as healthy working hours.
If that sounds like fun to you, please apply at https://careers.spacelift.io/jobs/3006934-software-engineer-...
You can find out more about the product we're building at https://spacelift.io and also see our engineering blog for a few technical blog posts of ours: https://spacelift.io/blog/engineering
We are hiring two Product Engineers to join us in our newly opened office in SF. We're small and early and you'll help shape team culture.
Kinelo solves "context myopia": autonomous and semi-autonomous AI agents don't know what they don't know, so they can't search or find the background information required to accomplish tasks accurately and effectively. The result looks like slop but it's not due to model performance, more due to workflow integration. From there, we're rapidly moving into organizing humans together with autonomous "AI coworkers" into workflows that span both. Our goal is to change how organizations are run and structured.
Our #1 hiring criteria for this position is immense software wisdom, the kind not yet encoded in the weights of an LLM. We are not looking for artisans to meticulously craft single lines of code. We're looking for software engineers excited to use the leverage that AI offers for code production to permit focus on higher order technical architecture, product requirements, and user needs.
We're looking for enough experience that indicates accumulated wisdom in shipping and maintaining reliable, scalable software, solid CS fundamentals, experience taking products from 0 to 1, and versatility.
Our current tech stack includes TypeScript, a managed container service, Postgres, and Redis. But we are adaptive and you should be too. We highly value software engineering and computer science fundamentals and experience with other languages like Go, C++, Python is valued.
Competitive salary, meaningful (~first batch of hires) equity, founder previously exited to Apple, strong fundraising history (~$10m).
Please email us at jobs@kinelo.com. If you want to stand out, tell us how you think the job of a software engineer is changing. There's also a full JD here: https://job-boards.greenhouse.io/kinelo/jobs/4205846009
Hey, I'm one of Stellar's founders. We're building AI for large contact centers, our primary product is voice.
Everyone thinks contact centers are boring. They're wrong. It's the last place where companies actually talk to their customers. We listen to calls every week and it's fascinating. AI here helps real people: shorter wait times, 24/7 support, lower cost. We’ve helped companies go from 60 to 98% pickup rate in weeks.
We're bootstrapped, 10 FTE, cash-flow positive, and growing fast with household names in the Netherlands and Belgium. Doubling our volume every month for the last 4 months.
We’re all builders. Everybody in our company still writes code. We have 2 roles open:
1. We need product minded engineers who can jump between our Go and TS backends and React frontend.
2. We need implementation leads that love working with clients. FDEs welcome as well.
This role is perfect if you:
* Want massive ownership at a small team
* Actually enjoy solving hard problems (real-time audio at enterprise scale)
* Think making AI sound human in niche dialects is a fun challenge
Find the full vacancies here: https://www.stellarcs.ai/careers
EU work authorization is required. No visa sponsorship available.
Apply: e-mail is in my profile, please indicate HN in your e-mail.
Join builds collaboration software for the construction industry — helping contractors, owners, and architects coordinate on high-value projects. React, Golang, Postgres. We deploy to AWS via Terraform.
We're hiring multiple senior/staff engineers across a range of profiles: frontend-heavy, fullstack, and backend-heavy. We're especially looking for 1–2 engineers with architect-level frontend chops (React, TypeScript, state management, perf) who can own UI quality and level up the team. But we're also very interested in strong Go/Postgres or infra/ops backgrounds.
Day to day you'll write code (25–75%), review PRs (25–50%), and pair/mentor/document (10–20%). You'll act as a technical lead on projects, break down large efforts, and influence architectural decisions across the org. Small cross-functional teams with a designer, PM, and EM.
Stack: React, TypeScript, Golang, Postgres, GraphQL/Apollo, Vite, Cypress, Terraform, AWS (ECS, RDS, Lambda). We lightly use Elastic and are interested in event-driven patterns.
Fully remote, 100% employer-paid medical, 401(k), two company-wide shutdown weeks, continuing education budget.
To apply: send resume to jon@join.build. If you are able to please include a PR review you've given that had a positive impact (or a description/snippet if that's confidential).
We're a Dental Support Organization running 59 practices across TX/OK/CO/MO/IA/NE/TN/AZ. The unsexy industry description hides what's actually an interesting technical role: a small dev team with real ownership, pushing hard on automation and AI to make dental operations actually work well.
Stack is primarily Rails 7.1 (Hotwire+Stimulus.js), with some React/Electron, C# .NET (OpenDental), and tiny bit of Go — all on AWS.
You'd be joining a tight team where developers own problems end-to-end: from understanding why a billing workflow breaks down, to designing the fix, to shipping it. The domain is surprisingly broad — patient communication, PMS integration, payroll, clinical workflows — and there's no shortage of genuinely novel problems once you learn the business.
Good fit if you like: stable company, small team, broad latitude, and work that visibly matters to the people using it. Not a fit if you need a large eng org — but there's plenty of greenfield work as we're still actively building new features, not just maintaining legacy code.
Drop me a line: dhanson [at] apexdp.com
At AllSpice, we're building the future of hardware development and collaboration, applying modern software design principles to the hardware industry with design review, automated test, and AI (think GitHub + copilot for hardware). AllSpice is unlocking the next generation of smart vehicles, IOT devices, rockets, medical devices, robotics, and much more.
Read more about our latest Series A announcement in TechCrunch (https://techcrunch.com/2025/06/23/allspices-platform-is-the-...)!
We have a highly capable, tight-knit, remote-first team with a flex office in Somerville, MA and SF. We strongly value continuous communication and personal development. See more on our careers page https://allspice.io/careers
We’re hiring primarily for:
Director of Software (Go, typescript, rust) - Hands-on leadership role (60/40% management to IC) spanning our Go, Rust, and Vue/TypeScript stack, where you'll own the technical roadmap, help make key architectural decisions, and build the team shaping the future of hardware development. https://www.allspice.io/careers?ashby_jid=7b9852d3-9aaf-4344...
Director of Infrastructure (Linux, Terraform, Docker, SOC 2) - Own our infrastructure stack, security posture, and compliance programs while building and leading a small, high-impact team. This is a hands-on leadership role (60/40 management to IC) requiring deep AWS and security expertise, experience working with legal counsel and enterprise customers, and the ability to hire and mentor as the team grows. https://www.allspice.io/careers?ashby_jid=88cf1665-04ab-4043...
LLM Platform Engineer (python, Typescript) - Build and own the internal tooling, analytics platforms, and customer-facing applications that power our Generative AI team, spanning evaluation dashboards, data pipelines, and lightweight web apps that surface AI-driven design review insights. This cross-functional role blends Python, TypeScript, and SQL across our LLM stack (Langchain, Pydantic AI, Langfuse) to give both internal teams and customers deep visibility into model performance and outcomes. https://www.allspice.io/careers?ashby_jid=6d5963b2-5c5e-4dec...
Head of Growth - Own and scale one AllSpice's enterprise demand & pipeline generation. https://www.allspice.io/careers?ashby_jid=b1ac9d68-2229-4005...
Tech Stack: Docker, Terraform, GoLang, Rust, Python, Vue, Typescript, Python
Please include any relevant open-source projects or portfolio in your application.
What we're looking for:
- Strong problem solvers who can work independently in a remote environment
- Security-minded professionals passionate about building robust, scalable systems
- Comfortable working during Eastern Time
Tech stack: Go, TypeScript, React, Kubernetes Open roles
* Application Software Engineer, Endpoint Security (macOS experience preferred)
* Fullstack Engineer, AI Implementation
* Senior Product Designer
* GTM Engineer
* Customer Support Specialist
We offer: - Competitive salary
- Equity in a fast growing cybersecurity startup
- 100% remote work
- Company offsites yearly (past offsites have been in The Netherlands, Portugal and Italy)
If you're interested in joining our team, please reach out to join<at>oneleet<dot>com with the subject line "HN: <Job Title>" and your resume attached. Alternatively, you can also apply at https://jobs.ashbyhq.com/oneleet
Additional Note: We are also building out a 'forward deployed' sales team based in San Fransisco - if interested, please reach out to join<at>oneleet<dot>com with the subject line of `HN: SF Sales`
Ema is building the Universal AI Employee — AI that handles repetitive enterprise tasks so people can focus on creative, high-impact work. Founded by ex-Google and Coinbase execs. $75M raised from Accel, Section 32, Prosus, KPMG, and others.
We're hiring software engineers to build the core platform: APIs, backend systems, data infrastructure, and front-end interfaces.
Stack: Go, Python, PostgreSQL, ClickHouse, Elasticsearch. Multi-tenant SaaS.
You'd be a great fit if you care about clean, test-driven code, have experience with enterprise integrations and auth, and thrive in a fast-moving startup where scope is broad and ambiguity is the norm.
Comp includes salary + equity + benefits, scaled to experience and level.