The Vera C. Rubin Observatory in Chile is a new world-class astronomy facility designed to create a 10-year time-lapse map of the southern sky. Featuring the world’s largest digital camera it emits 20GB of raw pixels per minute, and we are developing the Prompt Processing System that will distribute an alert on every astrophysical object that has moved, changed or appeared in real-time. (https://rubinobservatory.org/news/first-alerts)
This appointment is based at SLAC, a DOE-funded national laboratory hosting the data facility and many of the 80 scientists and engineers of the world-wide Rubin Data Management team. (https://www6.slac.stanford.edu/)
Keep Rubin's Alert Stream flowing. We are hiring an SRE to own the reliability of our Prompt Processing Framework, a Kubernetes-based, event-driven system using KEDA, Redis Streams, Kafka, and Postgres to scale near-real-time processing. You’ll write software to improve resilience, operate and evolve core infrastructure services, and build the monitoring, alerting, and on-call practices that keep the system robust and reliable during nightly observing operations.
Stack: Python, Kubernetes, Helm, ArgoCD, Kafka, Redis, KEDA, InfluxDB, PostgreSQL, Cassandra.
Details and apply here: ls.st/sre-ad
BillionToOne builds molecular diagnostics that detect disease at the single-molecule level. Our prenatal test is the only non-invasive screen for both recessive conditions and aneuploidies from one blood draw. Our oncology platform finds 50%+ more cancer treatment options than standard testing. Over 1 million tests processed to date. Every line of code here has a patient on the other end of it.
Revenue grew from $0 to ~$300M in four years, guiding $415-430M for 2026. Publicly traded and GAAP profitable. You'll work alongside clinicians and computational biologists on genuinely hard problems: scaling genomic pipelines, building digital infrastructure for complex test results, and shipping systems where correctness isn't optional.
Hiring across software engineering:
- Senior Software Engineer, Digital Experiences (Oncology and Prenatal)
- Senior Software Engineer, Oncology
- Senior Software Engineer, Prenatal
- Senior AI Engineer
Stack: Python, Django, Postgres, React, TypeScript, AWS, Docker, Terraform, Kafka, CircleCI, Datadog. AI-assisted dev tools (Cursor, Copilot, Claude Code).
Benefits: Access to the latest AI tools and models with unlimited usage to help you do your best work, 100% paid medical on select plans, 16 weeks fully paid parental leave, 401(k) with 4% match, daily catered lunch, on-site gym. Forbes Best Startup Employers 2024 & 2025.